2-Deoxyuridine-1,2,3,4,5-13C5
2-Deoxyuridine-1,2,3,4,5-13C5 is the 13C-labeled 2'-Deoxyuridine (HY-D0186) . 2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411) . 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) [1][2][3].
Product Specifications
CAS Number
[478510-94-0]
UNSPSC
12352005
Target
Endogenous Metabolite; Isotope-Labeled Compounds; Thymidylate Synthase
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O[13C@H]1[13CH2][13C@@H](O[13C@@H]1[13CH2]O)N(C(N2)=O)C=CC2=O
Molecular Formula
C4 13C5H12N2O5
Molecular Weight
233.17
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
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