1-Linoleoyl Glycerol-d5

1-Linoleoyl Glycerol-d5 (1-Linoleoyl-rac-glycerol-d5; 1-Monolinolein-d5) is the deuterium labeled 1-Linoleoyl Glycerol (HY-111346) . 1-Linoleoyl glycerol is a LpPLA2 inhibitor. 1-Linoleoyl glycerol acts as a precursor for synthesizing various functional lipids, such as phospholipids. 1-Linoleoyl glycerol mitigates inflammation induced by Apolipoprotein CIII (reduction of IL-6) [1][2][3].

Product Specifications

CAS Number

[1795137-84-6]

Product Name Alternative

1-Linoleoyl-rac-glycerol-d5; 1-Monolinolein-d5

UNSPSC

12352211

Target

Apolipoprotein; Interleukin Related; Isotope-Labeled Compounds; Phospholipase

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

OC([2H])(C([2H])(C([2H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)[2H])O)[2H]

Molecular Formula

C21H33D5O4

Molecular Weight

359.55

References & Citations

[1]Archambault AS, et al. Biosynthesis of the Novel Endogenous 15-Lipoxygenase Metabolites N-13-Hydroxy-octodecadienoyl-ethanolamine and 13-Hydroxy-octodecadienoyl-glycerol by Human Neutrophils and Eosinophils. Cells. 2021 Sep 5;10 (9) :2322.|[2]Duan H, et al. Dose-dependent effect of Dendrobium officinale polysaccharide on anti-aging in Caenorhabditis elegans: A metabolomics analysis focused on lipid and nucleotide metabolism regulation. Food Bioscience, 2024, 61: 104615.|[3]Lee WS, et al. Lp-PLA2 inhibitory activities of fatty acid glycerols isolated from Saururus chinensis roots. Bioorg Med Chem Lett. 2005 Aug 1;15 (15) :3573-5.