Bisnoralcohol
Bisnoralcohol is a RANKL inhibitor with an IC50 of 2.325 μM. Bisnoralcohol can inhibit RANKL-induced osteoclastogenesis and exhibits antiosteoporosis activity[1].
Product Specifications
CAS Number
40736-33-2
UNSPSC
12352211
Target
RANKL/RANK
Related Pathways
NF-κB
Field of Research
Metabolic Disease
Smiles
C[C@@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]3[C@H]2CCC4=CC(CC[C@]34C)=O)CO
Molecular Formula
C22H34O2
Molecular Weight
330.50
References & Citations
[1]Zhang DJ, et al. Synthesis of Heterocyclic Ring-Fused Bisnoralcohol Derivatives as Novel Small-Molecule Antiosteoporosis Agents. J Med Chem. 2024 May 23;67 (10) :8271-8295.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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