Bisnoralcohol

Bisnoralcohol is a RANKL inhibitor with an IC50 of 2.325 μM. Bisnoralcohol can inhibit RANKL-induced osteoclastogenesis and exhibits antiosteoporosis activity[1].

Product Specifications

CAS Number

[40736-33-2]

UNSPSC

12352211

Target

RANKL/RANK

Related Pathways

NF-κB

Field of Research

Metabolic Disease

Smiles

C[C@@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]3[C@H]2CCC4=CC(CC[C@]34C)=O)CO

Molecular Formula

C22H34O2

Molecular Weight

330.50

References & Citations

[1]Zhang DJ, et al. Synthesis of Heterocyclic Ring-Fused Bisnoralcohol Derivatives as Novel Small-Molecule Antiosteoporosis Agents. J Med Chem. 2024 May 23;67 (10) :8271-8295.