16α-Hydroxy-11-keto prednisolone

16α-Hydroxy-11-keto prednisolone (compound M-X) is a metabolite of Budesonide (HY-13580) . Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist. Budesonide is a widely used for study of asthma, rhinitis, and inflammatory bowel disease[1].

Product Specifications

CAS Number

[3754-05-0]

UNSPSC

12352211

Target

Drug Metabolite; Glucocorticoid Receptor

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer; Inflammation/Immunology

Purity

99.09

Smiles

C[C@@]12[C@](C[C@H]([C@]2(O)C(CO)=O)O)([H])[C@@]3([H])[C@]([C@@]4(C(CC3)=CC(C=C4)=O)C)([H])C(C1)=O

Molecular Formula

C21H26O6

Molecular Weight

374.43

References & Citations

[1]Matabosch X, et al. Identification of budesonide metabolites in human urine after oral administration. Anal Bioanal Chem. 2012 Aug;404 (2) :325-40.