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(S) - (+) -Ketoprofen-13C, d3

(S) - (+) -Ketoprofen-13C, d3 is the deuterium and 13C-labeled S- (+) -Ketoprofen. S- (+) -Ketoprofen is a potent inhibitor of both COX-1 and COX-2 with IC50s of 1.9 and 27 nM, respectively.

Product Specifications

CAS Number

1330260-99-5

UNSPSC

12352005

Target

COX; Isotope-Labeled Compounds

Related Pathways

Immunology/Inflammation; Others

Field of Research

Inflammation/Immunology

Smiles

O=C(C1=CC=CC=C1)C2=CC([C@H]([13C]([2H])([2H])[2H])C(O)=O)=CC=C2

Molecular Formula

C15 13CH11D3O3

Molecular Weight

258.29

References & Citations

[1]Palomer A, et al. Modeling cyclooxygenase inhibition. Implication of active site hydration on the selectivity ofketoprofen analogues. J Med Chem. 2000 Jun 1;43 (11) :2280-4.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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