(S) - (+) -Ketoprofen-13C, d3
(S) - (+) -Ketoprofen-13C, d3 is the deuterium and 13C-labeled S- (+) -Ketoprofen (HY-B2137) . S- (+) -Ketoprofen is a potent inhibitor of both COX-1 and COX-2 with IC50s of 1.9 and 27 nM, respectively.
Product Specifications
CAS Number
[1330260-99-5]
UNSPSC
12352005
Target
COX; Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=CC=CC=C1)C2=CC([C@H]([13C]([2H])([2H])[2H])C(O)=O)=CC=C2
Molecular Formula
C15 13CH11D3O3
Molecular Weight
258.29
References & Citations
[1]Palomer A, et al. Modeling cyclooxygenase inhibition. Implication of active site hydration on the selectivity ofketoprofen analogues. J Med Chem. 2000 Jun 1;43 (11) :2280-4.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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