2,5-Deoxyfructosazine-13C4

2,5-Deoxyfructosazine-13C4 (NSC 270912-13C4) is the 13C-labeled 2,5-Deoxyfructosazine (HY-135078) . 2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50=~1.25 mM) .

Product Specifications

CAS Number

[1246815-27-9]

Product Name Alternative

NSC 270912-13C4

UNSPSC

12352005

Target

DNA/RNA Synthesis; Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Others

Smiles

OC[C@@H](O)[C@@H](O)[C@H](O)[13C]1=N[13CH]=[13C](C[C@H](O)[C@H](O)CO)N=[13CH]1

Molecular Formula

C8 13C4H20N2O7

Molecular Weight

308.27

References & Citations

[1]Henry, et al. Synthesis of water-compatible imprinted polymers of in situ produced fructosazine and 2,5-deoxyfructosazine. Talanta 99, 816-823 (2012) .