4-[ (7-Chloro-4-quinolinyl) amino]-1-pentanol-d4
4-[ (7-Chloro-4-quinolinyl) amino]-1-pentanol-d4 is the deuterium labeled Hydroxychloroquine Impurity E. Hydroxychloroquine Impurity E is the impurity of Hydroxychloroquine. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro[1][2][3].
Product Specifications
CAS Number
1215752-28-5
UNSPSC
12352005
Target
Isotope-Labeled Compounds; SARS-CoV; Toll-like Receptor (TLR)
Related Pathways
Anti-infection; Immunology/Inflammation; Others
Field of Research
Others
Smiles
CC(NC1=C2C=CC(Cl)=CC2=NC=C1)CC([2H])(C([2H])(O)[2H])[2H]
Molecular Formula
C14H13D4ClN2O
Molecular Weight
268.78
References & Citations
[1]Manzo C, et al. Psychomotor Agitation Following Treatment with Hydroxychloroquine. Drug Saf Case Rep. 2017 Dec;4 (1) :6.|[2]Lamphier M, et al. Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. Mol Pharmacol. 2014 Mar;85 (3) :429-40.|[3]Yao X, et al. In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) . Clin Infect Dis. 2020 Mar 9. pii: ciaa237.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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