Bexarotene-13C4
Bexarotene-13C4 (LGD1069-13C4) is the 13C-labeled Bexarotene (HY-14171) . Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors (RXR) agonist with EC50s of 33, 24, 25 nM for RXRα, RXRβ, and RXRγ, respectively. Bexarotene shows limited affinity for RAR receptors (EC50 >10000 nM) [1][2][3]. Bexarotene can be used for the research of cutaneous T-cell lymphoma.
Product Specifications
CAS Number
[1185030-01-6]
Product Name Alternative
LGD1069-13C4
UNSPSC
12352005
Target
Autophagy; Isotope-Labeled Compounds; RAR/RXR
Related Pathways
Autophagy; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
C=C(C1=CC2=C(C([13CH3])(CCC2([13CH3])[13CH3])[13CH3])C=C1C)C3=CC=C(C=C3)C(O)=O
Molecular Formula
C20 13C4H28O2
Molecular Weight
352.45
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
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