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Bexarotene-13C4

Bexarotene-13C4 (LGD1069-13C4) is the 13C-labeled Bexarotene. Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors (RXR) agonist with EC50s of 33, 24, 25 nM for RXRα, RXRβ, and RXRγ, respectively. Bexarotene shows limited affinity for RAR receptors (EC50 >10000 nM)[2][3]. Bexarotene can be used for the research of cutaneous T-cell lymphoma.

Product Specifications

CAS Number

1185030-01-6

Product Name Alternative

LGD1069-13C4

UNSPSC

12352005

Target

Autophagy; Isotope-Labeled Compounds; RAR/RXR

Related Pathways

Autophagy; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Smiles

C=C(C1=CC2=C(C([13CH3])(CCC2([13CH3])[13CH3])[13CH3])C=C1C)C3=CC=C(C=C3)C(O)=O

Molecular Formula

C20 13C4H28O2

Molecular Weight

352.45

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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