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IDO-IN-7-d10

IDO-IN-7-d10 (NLG-919 analogue-d10; GDC-0919 analogue-d10) is the deuterium labeled IDO-IN-7. IDO-IN-7 (NLG-919 analogue) is a a potent IDO1 inhibitor with an IC50 of 38 nM.

Product Specifications

CAS Number

2058287-47-9

Product Name Alternative

NLG-919 analogue-d10; GDC-0919 analogue-d10

UNSPSC

12352005

Target

Indoleamine 2,3-Dioxygenase (IDO) ; Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

OC(CC1N2C(C3=C1C=CC=C3)=CN=C2)C4C([2H])(C([2H])(C([2H])(C([2H])(C4([2H])[2H])[2H])[2H])[2H])[2H]

Molecular Formula

C18H12D10N2O

Molecular Weight

292.44

References & Citations

[1]Coletti A, et al. Fragment-based approach to identify IDO1 inhibitor building blocks. Eur J Med Chem. 2017 Dec 1;141:169-177.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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