IDO-IN-7-d10
IDO-IN-7-d10 (NLG-919 analogue-d10; GDC-0919 analogue-d10) is the deuterium labeled IDO-IN-7 (HY-13983) . IDO-IN-7 (NLG-919 analogue) is a a potent IDO1 inhibitor with an IC50 of 38 nM.
Product Specifications
CAS Number
[2058287-47-9]
Product Name Alternative
NLG-919 analogue-d10; GDC-0919 analogue-d10
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO) ; Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
OC(CC1N2C(C3=C1C=CC=C3)=CN=C2)C4C([2H])(C([2H])(C([2H])(C([2H])(C4([2H])[2H])[2H])[2H])[2H])[2H]
Molecular Formula
C18H12D10N2O
Molecular Weight
292.44
References & Citations
[1]Coletti A, et al. Fragment-based approach to identify IDO1 inhibitor building blocks. Eur J Med Chem. 2017 Dec 1;141:169-177.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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