CF 1743-d7

CF 1743-d7 is the deuterium labeled Cf1743 (HY-107025) . Cf1743 is a potent anti-varicella-zoster virus (VZV) bicyclic nucleoside analogue. Cf1743 has antiviral activity, with an IC50 of 3.3 μM for VZV thymidine kinase (TK) [1].

Product Specifications

UNSPSC

12352005

Target

Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Infection

Smiles

O[C@H]1C[C@@H](O[C@@H]1CO)N2C=C3C(OC(C4=CC=C(C=C4)CCC([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])=C3)=NC2=O

Molecular Formula

C22H19D7N2O5

Molecular Weight

405.50

References & Citations

[1]McGuigan C, et al. 2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743. Bioorg Med Chem Lett. 2009 Nov 15;19 (22) :6264-7.