CF 1743-d7
CF 1743-d7 is the deuterium labeled Cf1743. Cf1743 is a potent anti-varicella-zoster virus (VZV) bicyclic nucleoside analogue. Cf1743 has antiviral activity, with an IC50 of 3.3 μM for VZV thymidine kinase (TK).
Product Specifications
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Infection
Smiles
O[C@H]1C[C@@H](O[C@@H]1CO)N2C=C3C(OC(C4=CC=C(C=C4)CCC([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])=C3)=NC2=O
Molecular Formula
C22H19D7N2O5
Molecular Weight
405.50
References & Citations
[1]McGuigan C, et al. 2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743. Bioorg Med Chem Lett. 2009 Nov 15;19 (22) :6264-7.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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