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Asenapine-13C, d3 (maleate)

Asenapine-13C, d3 Maleate is the deuterium labeled and 13C-Asenapine Maleate. Asenapine (Org 5222) Maleate, an atypical antipsychotic, is an antagonist of serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4) and histamine receptors (pKi: 8.2-9.0). Asenapine Maleate can be used in the research of schizophrenia and bipolar disorder[1][2].

Product Specifications

Product Name Alternative

Org 5222-13C, d3 (maleate)

UNSPSC

12352005

Target

5-HT Receptor; Adrenergic Receptor; Dopamine Receptor; Histamine Receptor; Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others

Applications

COVID-19-immunoregulation

Field of Research

Others

Smiles

[H][C@@]12C3=C(OC4=C([C@]1(CN(C2)[13C]([2H])([2H])[2H])[H])C=CC=C4)C=CC(Cl)=C3.OC(/C=C/C(O)=O)=O

Molecular Formula

C20 13CH17D3ClNO5

Molecular Weight

405.85

References & Citations

[1]Shahid M, et al. Asenapine: a novel psychopharmacologic agent with a unique human receptor signature. J Psychopharmacol. 2009 Jan;23 (1) :65-73.|[2]Olivia Frånberg, et al. Asenapine, a novel psychopharmacologic agent: preclinical evidence for clinical effects in schizophrenia. Psychopharmacology (Berl) . 2008 Feb;196 (3) :417-29.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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