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Sanguinarine (chloride) -13C, d3

Sanguinarine chloride-13C, d3 (Sanguinarin chloride-13C, d3) is the deuterium labeled Sanguinarine chloride (HY-N0052A) . Sanguinarine (Sanguinarin) chloride, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS) . Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.

Product Specifications

Product Name Alternative

Sanguinarin (chloride) -13C, d3; Sanguinarium (chloride) -13C, d3; Pseudochelerythrine (chloride) -13C, d3

UNSPSC

12352005

Target

Apoptosis; Autophagy; Bacterial; Isotope-Labeled Compounds; Parasite

Related Pathways

Anti-infection; Apoptosis; Autophagy; Others

Field of Research

Cancer

Smiles

[2H][13C]([2H])([N+]1=CC2=C(C3=C1C4=CC5=C(C=C4C=C3)OCO5)C=CC6=C2OCO6)[2H].[Cl-]

Molecular Formula

C19 13CH11D3ClNO4

Molecular Weight

371.79

References & Citations

[1]Wang Y, Noninvasive bioluminescence imaging of the dynamics of sanguinarine induced apoptosis via activation of reactive oxygen species. Oncotarget. 2016 Apr 19;7 (16) :22355-67.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Curated Selection

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