Cyclic GMP (sodium) -13C5
Cyclic GMP sodium-13C5 is the 13C-labeled Cyclic GMP sodium. Cyclic GMP (cGMP) sodium, an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP sodium occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses[1][2][3][4].
Product Specifications
UNSPSC
12352005
Target
Endogenous Metabolite; Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology; Cardiovascular Disease
Smiles
O=P1(O[13CH2][13C@@H]2[13C@]([H])([13C@H]([13C@@H](O2)N3C=NC4=C3N=C(N)NC4=O)O)O1)O[Na]
Molecular Formula
C5 13C5H11N5NaO7P
Molecular Weight
372.15
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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