8-Bromo-2'-deoxyguanosine-13C,15N2
8-Bromo-2'-deoxyguanosine-13C,15N2 is the 13C- and 15N-labeled 8-Bromo-2'-deoxyguanosine (HY-W011168) . 8-Bromo-2'-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog
Related Pathways
Cell Cycle/DNA Damage; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1C2=C(N=[13C]([15NH]1)[15NH2])N([C@H]3C[C@@H]([C@H](O3)CO)O)C(Br)=N2
Molecular Formula
C9 13CH12BrN3 15N2O4
Molecular Weight
349.12
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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