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C6 Ceramide-13C2, d2

C6 Ceramide-13C2, d2 (C6-Cer-13C2, d2) is the deuterium labeled and 13C-labeled C6 Ceramide (HY-19542) . C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator with anticancer activity. C6 Ceramide-mediated miR-29b expression participates in the progression of multiple myeloma through suppressing the proliferation, migration and angiogenesis of endothelial cells by targeting Akt signal pathway. C6 Ceramide exhibits multiple anti-cancer properties including cell cycle arrest, Apoptosis, inhibition of tumor growth and enhances the effects of chemotherapy in drug-resistant cancer cells. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects[1][2][3][4][5].

Product Specifications

Product Name Alternative

C6-Cer-13C2, D2; N-Hexanoylsphingosine-13C2, d2

UNSPSC

12352211

Target

Apoptosis; Isotope-Labeled Compounds

Related Pathways

Apoptosis; Others

Field of Research

Cancer

Smiles

CCCCCCCCCCCCC/C=C/[C@H]([13C@H]([13C]([2H])(O)[2H])NC(CCCCC)=O)O

Molecular Formula

C22 13C2H45D2NO3

Molecular Weight

401.63

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Curated Selection

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