1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin

1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin is a polychlorinated dibenzo-p-dioxin (PCDD) congener. 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin can cause pale (fatty) livers, gastrointestinal hemorrhage and early death in H/W and line A rats at the highest dose (10,000 μg/kg) . 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin also induces sinusoidal distension, and even severe peliosis in line B[1].

Product Specifications

CAS Number

[39227-28-6]

Product Name Alternative

1,2,3,4,7,8-HxCDD

UNSPSC

12352005

Hazard Statement

H301-H319-H335-H341-H410

Target

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Metabolic Disease

Smiles

ClC1=C(Cl)C=C2C(OC3=C(Cl)C(Cl)=C(Cl)C(Cl)=C3O2)=C1

Molecular Formula

C12H2Cl6O2

Molecular Weight

390.86

Precautions

P261-P264-P270-P271-P273-P280-P304+P340-P305+P351+P338-P330-P391-P403+P233-P405-P501

References & Citations

[1]Niittynen M, et al. Differences in acute toxicity syndromes of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin in rats. Toxicology. 2007 Jun 3;235 (1-2) :39-51.