1- (4-Pip-Ph) -DHP-dione
1- (4-Pip-Ph) -DHP-dione is an E3 ligase ligand. 1- (4-Pip-Ph) -DHP-dione can be used for synthesis of PROTAC HPK1 Degrader-2 (HY-162544) [1].
Product Specifications
CAS Number
[2446913-96-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Others
Purity
99.04
Smiles
O=C1NC(CCN1C2=CC=C(N3CCNCC3)C=C2)=O
Molecular Formula
C14H18N4O2
Molecular Weight
274.32
Precautions
H302, H315, H319, H335
References & Citations
[1]BeiGene, Ltd. Preparation of pyrrolo[2,3-b]pyrazine-based bifunctional compounds as HPK1 degraders and the use thereof. World Intellectual Property Organization, WO2023006063 A1 2023-02-02.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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