3-Iodothyronamine (hydrochloride) -13C6

3-Iodothyronamine hydrochloride-13C6 is the 13C-labeled 3-Iodothyronamine hydrochloride (HY-135065) . 3-Iodothyronamine hydrochloride is an endogenous and rapid-acting derivative of thyroid hormone. 3-Iodothyronamine potently activates an orphan G protein-coupled receptor in vitro (TAAR1) and induced hypothermia in vivo on a rapid time scale. 3-Iodothyronamine can be used for the research of congestive heart failure[1].

Product Specifications

CAS Number

[2724727-67-5]

UNSPSC

12352005

Target

Isotope-Labeled Compounds; Trace Amine-associated Receptor (TAAR)

Related Pathways

GPCR/G Protein; Others

Field of Research

Metabolic Disease

Smiles

NCCC1=CC=C(C(I)=C1)O[13C]2=[13CH][13CH]=[13C]([13CH]=[13CH]2)O.Cl

Molecular Formula

C8 13C6H15ClINO2

Molecular Weight

397.59

References & Citations

[1]Hart ME, et al. Trace amine-associated receptor agonists: synthesis and evaluation of thyronamines and related analogues. J Med Chem. 2006 Feb 9;49 (3) :1101-12.