ALK ligand-1
ALK ligand-1 is a ALK ligand that can be used for synthesis of PROTAC ALK degrader-4 (HY-175527) [1].
Product Specifications
CAS Number
[2353496-79-2]
UNSPSC
12352005
Target
Anaplastic lymphoma kinase (ALK) ; Ligands for Target Protein for PROTAC
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
CCC(C=C1C(C(C)(C2=C(C1=O)C(C=CC(C#N)=C3)=C3N2)C)=C4)=C4N(CC5)CCC5N6CCNCC6
Molecular Formula
C30H35N5O
Molecular Weight
481.63
References & Citations
[1]Xie S, et al. Overcoming E3 Ligase-Mediated Resistance: Development of Novel Hydrophobic Tagging-Based Degraders Targeting ALK Protein. J Med Chem. 2025 Aug 14;68 (15) :15579-15597.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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