2-Formyl sunitinib

2-Formyl sunitinib (1-CHO) is a metabolite of tyrosine kinase inhibitor Sunitinib (HY-10255A) . 2-Formyl sunitinib can be used for the research of cancer[1].

Product Specifications

CAS Number

[2377533-92-9]

UNSPSC

12352005

Target

Drug Metabolite

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

O=C(/C(C1=C2)=C\C3=C(C(C(NCCN(CC)CC)=O)=C(N3)C=O)C)NC1=CC=C2F

Molecular Formula

C22H25FN4O3

Molecular Weight

412.46

References & Citations

[1]Paludetto MN, et al. Metalloporphyrin-Catalyzed Oxidation of Sunitinib and Pazopanib, Two Anticancer Tyrosine Kinase Inhibitors: Evidence for New Potentially Toxic Metabolites. J Med Chem. 2018 Sep 13;61 (17) :7849-7860.