Cytidine-5'-triphosphate-13C5

Cytidine-5'-triphosphate-13C5 (Cytidine triphosphate-13C5) is the 13C-labeled Cytidine-5'-triphosphate (HY-125818) . Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP) . Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii[1].

Product Specifications

CAS Number

[200258-75-9]

Product Name Alternative

Cytidine triphosphate-13C5; 5'-CTP-13C5; Cytidine-5'-triphosphate-1',2',3',4',5'-13C5 Triethylamine Salt

UNSPSC

12352005

Target

DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

O[13C@H]1[13C@@H](O[13C@@H]([13C@H]1O)[13CH2]OP(OP(OP(O)(O)=O)(O)=O)(O)=O)N2C=CC(N)=NC2=O

Molecular Formula

C4 13C5H16N3O14P3

Molecular Weight

488.12

References & Citations

[1]Heidy Y Narvaez-Ortiz, et al. A CTP Synthase Undergoing Stage-Specific Spatial Expression Is Essential for the Survival of the Intracellular Parasite Toxoplasma gondii. Front Cell Infect Microbiol. 2018 Mar 22;8:83.|[2]Hatch GM, et al., Regulation of cardiolipin biosynthesis in H9c2 cardiac myoblasts by cytidine 5'-triphosphate. J Biol Chem. 1996 Oct 18;271 (42) :25810-6.|[3]Matsumoto S, et al., An equilibrium binding study of the interaction of aspartate transcarbamylase with cytidine 5'-triphosphate and adenosine 5'-triphosphate. Biochemistry. 1973 Mar 27;12 (7) :1388-94.