N4-Acetylcytidine-13C5
N4-Acetylcytidine-13C5 is the 13C-labeled N4-Acetylcytidine (HY-W019670) . N4-acetylcytidine (N4A) is an endogenous nucleoside metabolite from the degradation of tRNA. N4-Acetylcytidine is formed by N-acetyltransferase 10 and other enzymes. N4-acetylcytidine might sustain NLRP3 inflammasome activation via induction of HMGB1 expression and releasee. N4-Acetylcytidine modifies mRNA, tRNA and rRNA, affecting their stability, translation efficiency (such as enterovirus 71 RNA) . N4-Acetylcytidine is used in the study of cancer, neuroinflammatory diseases, viral infections and obesity[1][2][3][4][5].
Product Specifications
UNSPSC
12352005
Target
Endogenous Metabolite; Enterovirus; Histone Acetyltransferase; Isotope-Labeled Compounds; NOD-like Receptor (NLR)
Related Pathways
Anti-infection; Epigenetics; Immunology/Inflammation; Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Purity
95.92
Smiles
O=C(N=C(NC(C)=O)C=C1)N1[13C@@H]2O[13C@H]([13CH2]O)[13C@@H](O)[13C@H]2O
Molecular Formula
C6 13C5H15N3O6
Molecular Weight
290.22
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W753593/N4-Acetylcytidine-13C5-SDS-MedChemExpress.pdf
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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