15-Keto Fluprostenol

15-keto Fluprostenol is a derivative of the FP receptor agonist fluprostenol that is oxidized at carbon.

Product Specifications

CAS Number

[2136344-22-2]

UNSPSC

12352005

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Smiles

FC(F)(F)C1=CC=CC(OCC(/C=C/[C@@H]2[C@H]([C@H](C[C@H]2O)O)C/C=C\CCCC(O)=O)=O)=C1

Molecular Formula

C23H27F3O6

Molecular Weight

456.45

References & Citations

[1]Fujimori, K., Okada, T., and Urade, Y. Expression of NADP+-dependent 15-hydroxyprostaglandin dehydrogenase mRNA in monkey ocular tissues and characterization of its recombinant enzyme. J. Biochem. 131 (3), 383-389 (2002) .|[2]Asendrych-Wicik, K., Zarczuk, J., Walaszek, K., et al. Trends in development and quality assessment of pharmaceutical formulations - F2α analogues in the glaucoma treatment. Eur. J. Pharm. Sci. 180, 106315 (2023) .