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Orthosporin

Orthosporin ((+) -Orthosporin), a phytotoxic isocoumarin compound, is a microbial secondary metabolite. Orthosporin can be isolated from the endophytic fungus Lasiodiplodia tbeobromae. Orthosporin has potent antibacterial activity against B. subtilis, E. coli and P. aeruginosa. Orthosporin also has antioxidant activity against DPPH radical and antiviral activities with inhibition of HIV-1 reverse transcriptase activity[1].

Product Specifications

CAS Number

118063-79-9

Product Name Alternative

(+) -Orthosporin

UNSPSC

12352005

Target

Bacterial; Endogenous Metabolite; HIV; Reverse Transcriptase

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

O=C1C2=C(C=C(C=C2C=C(C[C@H](C)O)O1)O)O

Molecular Formula

C12H12O5

Molecular Weight

236.22

References & Citations

[1]Okezie U M, et al. Orthosporin, a major component of the fermentation product of Lasiodiplodia theobromae-an endophytic fungus of Musa paradisiaca as a potential antimicrobial agent[J]. Notulae Scientia Biologicae, 2022, 14 (2) : 11084-11084.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

HIV-1

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