9-cis-Canthaxanthin
9-cis-Canthaxanthin is a carotenoid with pro-apoptotic activity in THP-1 macrophage cells. 9-cis-Canthaxanthin induces cell apoptosis by increasing caspase-3 and caspase-8 activity[1].
Product Specifications
CAS Number
[101915-55-3]
UNSPSC
12352211
Target
Apoptosis; Caspase
Related Pathways
Apoptosis
Field of Research
Inflammation/Immunology
Smiles
CC(C)(CC1)C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)\C=C\C(C(C)(CC2)C)=C(C)C2=O)=C(C)C1=O
Molecular Formula
C40H52O2
Molecular Weight
564.84
References & Citations
[1]Venugopalan V, et al. 9-cis-canthaxanthin exhibits higher pro-apoptotic activity than all-trans-canthaxanthin isomer in THP-1 macrophage cells. Free Radic Res. 2009 Feb;43 (2) :100-5.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Caspase 3; Caspase 8
Curated Selection
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