Bleomycin B2

Bleomycin B2 (Phleomycin D2) is an anti-cancer agent that targets DNA. Bleomycin B2 causes DNA strand breaks, thereby inhibiting the growth and proliferation of cancer cells. Bleomycin B2 is promising for research of cancers[1].

Product Specifications

CAS Number

[9060-10-0]

Product Name Alternative

Phleomycin D2

UNSPSC

12352005

Target

DNA Stain

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O=C(C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C)N[C@H](C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@@H]([C@H](O)C)C(NCCC2=NC(C3=NC(C(NCCCCNC(N)=N)=O)=CS3)=CS2)=O)=O)=O)[C@H](C4=CN=CN4)O[C@H]5[C@H]([C@H]([C@@H]([C@@H](O5)CO)O)O)O[C@@H]6[C@H]([C@H]([C@@H]([C@H](O6)CO)O)OC(N)=O)O

Molecular Formula

C55H84N20O21S2

Molecular Weight

1425.51

References & Citations

[1]Gu J, et al. Copper (II) -based metal affinity chromatography for the isolation of the anticancer agent bleomycin from Streptomyces verticillus culture. J Inorg Biochem. 2012 Oct;115:198-203.