TAN-420E
TAN-420E (Dihydroherbimycin A) is an antibiotic, that can be isolated from the fermentation product of Streptomyces hygroscopicus. TAN-420E exhibits cytotoxicity in cancer cells P-388 and KB. TAN-420E scavenges DPPH free radicals with an IC50 of 1.3 μM[1][2].
Product Specifications
CAS Number
91700-93-5
Product Name Alternative
Dihydroherbimycin A
UNSPSC
12352005
Target
Antibiotic; Reactive Oxygen Species (ROS)
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer; Infection
Smiles
C[C@H]1C[C@H](OC)[C@H](OC)[C@@H](C)/C=C(C)/[C@H](OC(N)=O)[C@@H](OC)/C=C\C=C(C)\C(NC2=C(O)C([C@@H]1OC)=CC(O)=C2)=O
Molecular Formula
C30H44N2O9
Molecular Weight
576.68
References & Citations
[1]Lin LZ, et al., 1H-nmr analysis of herbimycins and dihydro-herbimycins. J Nat Prod. 1988 Nov-Dec;51 (6) :1161-5|[2]Chang HB, et al., Antioxidant properties of dihydroherbimycin A from a newly isolated Streptomyces sp. Biotechnol Lett. 2007 Apr;29 (4) :599-603.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PKSV030351 100 µg
Recombinant SARS-CoV-2 Spike RBD (S494P) (His Tag)
Sign In for Pricing
View Details