Epibetulinic acid-d3

Epibetulinic acid-d3 is the deuterium labeled Epibetulinic acid (HY-N0223) . Epibetulinic acid exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1].

Product Specifications

UNSPSC

12352211

Target

Isotope-Labeled Compounds; NO Synthase; Prostaglandin Receptor

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Others

Field of Research

Inflammation/Immunology

Smiles

[H][C@]12[C@](C)([C@@]3(CC[C@]4(C(C)([C@@]([2H])(C([2H])(C[C@@]4([C@]3(CC2)[H])C)[2H])O)C)[H])C)CC[C@@]5([C@@]1([C@@H](CC5)C(C)=C)[H])C(O)=O

Molecular Formula

C30H45D3O3

Molecular Weight

459.72

References & Citations

[1]Reyes CP, et al. Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2. Bioorg Med Chem. 2006 Mar 1;14 (5) :1573-9.