Epibetulinic acid-d3
Epibetulinic acid-d3 is the deuterium labeled Epibetulinic acid. Epibetulinic acid exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1].
Product Specifications
UNSPSC
12352211
Target
Isotope-Labeled Compounds; NO Synthase; Prostaglandin Receptor
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology
Smiles
[H][C@]12[C@](C)([C@@]3(CC[C@]4(C(C)([C@@]([2H])(C([2H])(C[C@@]4([C@]3(CC2)[H])C)[2H])O)C)[H])C)CC[C@@]5([C@@]1([C@@H](CC5)C(C)=C)[H])C(O)=O
Molecular Formula
C30H45D3O3
Molecular Weight
459.72
References & Citations
[1]Reyes CP, et al. Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2. Bioorg Med Chem. 2006 Mar 1;14 (5) :1573-9.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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