(±) -Darifenacin N-Oxide
(±) -Darifenacin N-Oxide is the impurity of Darifenacin (HY-A0033) . Darifenacin (UK-88525) is a selective and orally active M3 muscarinic receptor (M3R) antagonist with a pKi of 8.9[1].
Product Specifications
CAS Number
[2416229-88-2]
UNSPSC
12352005
Target
MAChR
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(N)C(C1C[N+](CCC2=CC=C(OCC3)C3=C2)([O-])CC1)(C4=CC=CC=C4)C5=CC=CC=C5
Molecular Formula
C28H30N2O3
Molecular Weight
442.55
References & Citations
[1]Hegde SS, et al. Functional role of M2 and M3 muscarinic receptors in the urinary bladder of rats in vitro and in vivo. Br J Pharmacol. 1997 Apr;120 (8) :1409-18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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