(±) -Darifenacin N-Oxide

(±) -Darifenacin N-Oxide is the impurity of Darifenacin (HY-A0033) . Darifenacin (UK-88525) is a selective and orally active M3 muscarinic receptor (M3R) antagonist with a pKi of 8.9[1].

Product Specifications

CAS Number

[2416229-88-2]

UNSPSC

12352005

Target

MAChR

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

O=C(N)C(C1C[N+](CCC2=CC=C(OCC3)C3=C2)([O-])CC1)(C4=CC=CC=C4)C5=CC=CC=C5

Molecular Formula

C28H30N2O3

Molecular Weight

442.55

References & Citations

[1]Hegde SS, et al. Functional role of M2 and M3 muscarinic receptors in the urinary bladder of rats in vitro and in vivo. Br J Pharmacol. 1997 Apr;120 (8) :1409-18.