D-Penicillamine-d6

D-Penicillamine-d6 is the deuterium labeled L-Penicillamine (HY-116073) . L-Penicillamine is a mechanism-based inhibitor of serine palmitoyltransferase by forming a pyridoxal-5 '-phosphate-thiazolidine adduct. L-Penicillamine is a metal chelating agent of intermediate strength[1][2].

Product Specifications

UNSPSC

12352211

Target

Biochemical Assay Reagents; Isotope-Labeled Compounds

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Smiles

SC([C@H](N)C(O)=O)(C([2H])([2H])[2H])C([2H])([2H])[2H]

Molecular Formula

C5H5D6NO2S

Molecular Weight

155.25

References & Citations

[1]Roland Degenkolbe, et al. Chelating agents stabilize the monomeric state of the zinc binding human papillomavirus 16 E6 oncoprotein. Biochemistry. 2003 Apr 8;42 (13) :3868-73. |[2]Jonathan Lowther, et al. L-Penicillamine is a mechanism-based inhibitor of serine palmitoyltransferase by forming a pyridoxal-5 '-phosphate-thiazolidine adduct. Med. Chem. Commun., 2012,3, 1003-1008.