L-2-Hydroxyglutaric acid-d5 (disodium)
L-2-Hydroxyglutaric acid-d5 disodium ((2S) -2-Hydroxyglutaric acid-d5 disodium) is the deuterium labeled L-2-Hydroxyglutaric acid disodium. L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid disodium can inhibit histone demethylases and hence promote histone methylation[1]. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively[2].
Product Specifications
Product Name Alternative
(2S) -2-Hydroxyglutaric acid-d5 (disodium)
UNSPSC
12352211
Target
Endogenous Metabolite; Histone Demethylase; Isotope-Labeled Compounds; Mitochondrial Metabolism
Related Pathways
Epigenetics; Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
O=C(O[Na])C([2H])(C([2H])([C@](O)(C(O[Na])=O)[2H])[2H])[2H]
Molecular Formula
C5HD5Na2O5
Molecular Weight
197.11
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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