2-Azidoethanol-d4

2-Azidoethanol-d4 is the deuterium labeled Azido-PEG1 (HY-138461) . Azido-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

UNSPSC

12352211

Target

Isotope-Labeled Compounds; PROTAC Linkers

Related Pathways

Others; PROTAC

Field of Research

Cancer

Smiles

OC([2H])(C([2H])(N=[N+]=[N-])[2H])[2H]

Molecular Formula

C2HD4N3O

Molecular Weight

91.11

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562