3′-Oxolutein

3′-Oxolutein, a metabolite of dietary lutein, is an anti-inflammatory agent and antioxidant, 3′-Oxolutein mitigates the effects of glutamate-induced ROS production and proinflammatory cytokine secretions in SH-SY5Y cells. 3'-Oxolutein reduces glutamate-induced iron content and increases thiol levels. 3′-Oxolutein can be used for the study of inflammation[1].

Product Specifications

CAS Number

[23984-55-6]

Product Name Alternative

3'-Dehydrolutein; Philosamiaxanthin

UNSPSC

12352211

Target

Endogenous Metabolite; Reactive Oxygen Species (ROS)

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Smiles

CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/[C@@H]2C(C)(CC(C=C2C)=O)C)=C(C)C[C@@H](O)C1

Molecular Formula

C40H54O2

Molecular Weight

566.86

References & Citations

[1]Pap R, et al. Protective Effects of 3'-Epilutein and 3'-Oxolutein against Glutamate-Induced Neuronal Damage. Int J Mol Sci. 2023 Jul 26;24 (15) :12008.