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O-Arachidonoyl glycidol-d5

O-Arachidonoyl glycidol-d5 is the deuterium labeled O-Arachidonoyl glycidol (HY-131995) . O-Arachidonoyl glycidol (compound 1) is a 2-arachidonoylglycerol (2-AG) analog. O-Arachidonoyl glycidol inhibits cytosolic 2-oleoylglycerol (2-OG) hydrolysis with an IC50 value of 4.5 μM. O-Arachidonoyl glycidol blocks 2-OG hydrolysis in membrane fractions and anandamide hydrolysis with IC50s of 19, 12 μM, respectively[1].

Product Specifications

CAS Number

[2519458-54-7]

UNSPSC

12352005

Target

Cannabinoid Receptor; Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Metabolic Disease

Smiles

O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)OC([2H])(C1(OC1([2H])[2H])[2H])[2H]

Molecular Formula

C23H31D5O3

Molecular Weight

365.56

References & Citations

[1]Cisneros JA, et al. Structure-activity relationship of a series of inhibitors of monoacylglycerol hydrolysis--comparison with effects upon fatty acid amide hydrolase. J Med Chem. 2007 Oct 4;50 (20) :5012-23.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Curated Selection

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