Sulindac Sulfone-d6
Sulindac Sulfone-d6 is the deuterium labeled Sulindac sulfone. Sulindac sulfone is an mTORC1 pathway inhibitor and a metabolite of Sulindac. Sulindac sulfone inhibits colon cancer cell growth and induces cell cycle arrest. Sulindac sulfone is used in cancer research[1].
Product Specifications
CAS Number
2519512-94-6
UNSPSC
12352005
Target
Drug Metabolite; Isotope-Labeled Compounds; mTOR
Related Pathways
Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
FC1=CC=C2C(C(C([2H])(C(O)=O)[2H])=C(/C2=C(C3=CC=C(C=C3)S(=O)(C([2H])([2H])[2H])=O)\[2H])C)=C1
Molecular Formula
C20H11D6FO4S
Molecular Weight
378.45
References & Citations
[1]Aono Y, et al. Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting voltage-dependent anion channel 1 and 2. Biochem Biophys Res Commun. 2018 Nov 10;505 (4) :1203-1210.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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