4-Hydroxyphenylbutazone-d9

4-Hydroxyphenylbutazone-d9 is the deuterium labeled 4-Hydroxyphenylbutazone (HY-139199) . 4-Hydroxyphenylbutazone is a metabolite of Phenylbutazone. Phenylbutazone, a nonsteroidal anti-inflammatory agent (NSAID), is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS) [1].

Product Specifications

CAS Number

[1246819-23-7]

UNSPSC

12352005

Target

Drug Metabolite; Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Others

Smiles

[2H]C([2H])(C([2H])(C([2H])(C([2H])(C1(O)C(N(C2=CC=CC=C2)N(C3=CC=CC=C3)C1=O)=O)[2H])[2H])[2H])[2H]

Molecular Formula

C19H11D9N2O3

Molecular Weight

333.43

References & Citations

[1]Hughes MF, et, al. Prostaglandin hydroperoxidase-dependent oxidation of phenylbutazone: relationship to inhibition of prostaglandin cyclooxygenase. Mol Pharmacol. 1988 Aug;34 (2) :186-93.