Migalastat (hydrochloride) -15N
Migalastat hydrochloride-15N (GR181413A-15N) is the 15N-labeled Migalastat hydrochloride (HY-14929A) . Migalastat (GR181413A free base) hydrochloride is an orally active α-galactosidase A molecular chaperone, with an IC50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity[1].
Product Specifications
CAS Number
[1219134-37-8]
Product Name Alternative
GR181413A-15N
UNSPSC
12352005
Target
Glycosidase; Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Others
Smiles
O[C@H]1[C@H]([C@H]([15NH]C[C@@H]1O)CO)O.Cl
Molecular Formula
C6H14Cl 15NO4
Molecular Weight
200.63
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
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