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3'-Deoxy-3'-fluorothymidine-d3

3'-Deoxy-3'-fluorothymidine-d3 is the deuterium labeled Alovudine (HY-B1516) . Alovudine (3'-Fluoro-3'-deoxythymidine) is a mtDNA synthesis inhibitor and a marker of DNA synthesis. Alovudine is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer. Alovudine shows anti-orthopoxvirus and anti-leukemic activity[1][2][3][4][5][6].

Product Specifications

CAS Number

[1346523-18-9]

UNSPSC

12352005

Target

DNA/RNA Synthesis; Isotope-Labeled Compounds; Orthopoxvirus

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Others

Field of Research

Cancer

Smiles

O=C1C(C([2H])([2H])[2H])=CN(C(N1)=O)[C@H]2C[C@@H]([C@H](O2)CO)F

Molecular Formula

C10H10D3FN2O4

Molecular Weight

247.24

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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