4-Methoxy-d3 17b-estradiol

4-Methoxy-d3 17b-estradiol is the deuterium labeled 4-Methoxyestradiol (HY-148296) . 4-Methoxyestradiol is methoxylestradiol that induces oxidative DNA damage in human lung epithelial cells. 4-Methoxyestradiol also elevates ROS and SOD activities in H1355 cells[1].

Product Specifications

CAS Number

[1334143-12-2]

UNSPSC

12352005

Target

Reactive Oxygen Species (ROS)

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Cancer

Smiles

OC1=C(C2=C(C=C1)[C@@]([H])(CC[C@]3([C@]4(CC[C@@H]3O)[H])C)[C@@]4([H])CC2)OC([2H])([2H])[2H]

Molecular Formula

C19H23D3O3

Molecular Weight

305.43

References & Citations

[1]Yahsin Cheng, et al. 4-Methoxyestradiol-induced oxidative injuries in human lung epithelial cells. Toxicol Appl Pharmacol. 2007 May 1;220 (3) :271-7.