N-Desmethyl rosuvastatin (disodium hydrate)
N-Desmethyl rosuvastatin disodium hydrate is an active metabolite of HMG-CoA reductase (HMGCR) inhibitor rosuvastatin. N-Desmethyl rosuvastatin disodium hydrate can be utilized in research of rosuvastatin metabolism[1].
Product Specifications
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; Drug Metabolite; HMG-CoA Reductase (HMGCR)
Related Pathways
Autophagy; Metabolic Enzyme/Protease
Field of Research
Cancer; Metabolic Disease; Cardiovascular Disease
Smiles
O=C(O[Na])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C)C)N=C([N-]S(=O)(C)=O)N=C1C2=CC=C(F)C=C2.[Na+].O
Molecular Formula
C21H26FN3Na2O7S
Molecular Weight
529.49
Precautions
H302, H315, H319, H335
References & Citations
[1]Bai X, et al. Rosuvastatin, Rosuvastatin-5 S-lactone, and N-desmethyl Rosuvastatin in Human Plasma by UPLC-MS/MS and Its Application to Clinical Study. Drug Res (Stuttg) . 2018 Jun;68 (6) :328-334.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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