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2,3’-Anhydrothymidine-d3

2,3’-Anhydrothymidine-d3 (2’-Deoxy-3’,2-anhydro-5-methyluridine-d3) is the deuterium labeled 2,3’-Anhydrothymidine (HY-154340) . 2,3’-Anhydrothymidine; 2’-Deoxy-3’,2-anhydro-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

Product Name Alternative

2’-Deoxy-3’,2-anhydro-5-methyluridine-d3

UNSPSC

12352005

Target

Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Cancer

Smiles

OC[C@H]1O[C@@H]2C[C@H]1OC(N2C=C3C([2H])([2H])[2H])=NC3=O

Molecular Formula

C10H9D3N2O4

Molecular Weight

227.23

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

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