E3 ligase Ligand 50
E3 ligase Ligand 50 is the ligand for E3 ligase Cereblon. E3 ligase Ligand 50 can be used for synthesis of PROTAC BTK Degrader-10 (HY-160966) [1].
Product Specifications
CAS Number
[2758531-98-3]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
OCCC1=CC=C(C=C1)N2C(=O)NC(=O)CC2
Molecular Formula
C12H14N2O3
Molecular Weight
234.25
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Bian Z, et al., Pyrimidines for degrading bruton's tyrosine kinase. EP4249073.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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