E3 ligase Ligand 50

E3 ligase Ligand 50 is the ligand for E3 ligase Cereblon. E3 ligase Ligand 50 can be used for synthesis of PROTAC BTK Degrader-10 (HY-160966) [1].

Product Specifications

CAS Number

[2758531-98-3]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

OCCC1=CC=C(C=C1)N2C(=O)NC(=O)CC2

Molecular Formula

C12H14N2O3

Molecular Weight

234.25

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Bian Z, et al., Pyrimidines for degrading bruton's tyrosine kinase. EP4249073.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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