(R) - (-) -Citramalic acid (lithium)

(R) - (-) -Citramalic acid ((R) -Citramalate) lithium, a lithium salt of Citramalic acid, is the R enantiomer of Citramalic acid lithium. (R) - (-) -Citramalic acid lithium is involved in the metabolism of glutamate through the methylaspartate pathway. (R) - (-) -Citramalic acid lithium is promising for research of neurological disorders[1][2][3].

Product Specifications

CAS Number

[2319882-36-3]

Product Name Alternative

(R) -Citramalate (lithium) ; (2R) -Methylmalic acid (lithium)

UNSPSC

12352211

Target

Drug Isomer

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Neurological Disease

Smiles

O=C(O[Li])C[C@@](C)(O)C(O)=O

Molecular Formula

C5H7LiO5

Molecular Weight

154.05

References & Citations

[1]Whitesell J K, et al. Observations on the reactions of chiral pyruvates. Synthesis of (-) -and (+) -citramalic acid[J]. The Journal of Organic Chemistry, 1989, 54 (9) : 2258-2260.|[2]Howell DM, et al. (R) -citramalate synthase in methanogenic archaea. J Bacteriol. 1999 Jan;181 (1) :331-3.|[3]Gill M, et al. Pigments of fungi. LIX. Synthesis of (1S, 3S) -and (1R, 3R) -austrocortilutein and (1S, 3S) -austrocortirubin from citramalic acid[J]. Australian Journal of Chemistry, 2000, 53 (4) : 245-256.