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5'-DMT-5-F-2'-dU Phosphoramidite

2'-Deoxy-5'-O-DMT-5-fluorouridine 3'-CE phosphoramidite is a nucleoside phosphoramidite analogue employed in oligonucleotide synthesis. This compound contributes to crafting therapeutic oligonucleotides for drugs targeting cancers.

Product Specifications

CAS Number

142246-63-7

UNSPSC

12352005

Hazard Statement

H301, H311, H315, H319, H331, H335

Target

Nucleoside Antimetabolite/Analog

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1NC(C(F)=CN1[C@@H]2O[C@H](COC(C3=CC=C(C=C3)OC)(C4=CC=CC=C4)C5=CC=C(C=C5)OC)[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)C2)=O

Molecular Formula

C39H46FN4O8P

Molecular Weight

748.78

Precautions

H301, H311, H315, H319, H331, H335

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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