5'-DMT-5-F-2'-dU Phosphoramidite
2'-Deoxy-5'-O-DMT-5-fluorouridine 3'-CE phosphoramidite is a nucleoside phosphoramidite analogue employed in oligonucleotide synthesis. This compound contributes to crafting therapeutic oligonucleotides for drugs targeting cancers.
Product Specifications
CAS Number
[142246-63-7]
UNSPSC
12352005
Hazard Statement
H301, H311, H315, H319, H331, H335
Target
Nucleoside Antimetabolite/Analog
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1NC(C(F)=CN1[C@@H]2O[C@H](COC(C3=CC=C(C=C3)OC)(C4=CC=CC=C4)C5=CC=C(C=C5)OC)[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)C2)=O
Molecular Formula
C39H46FN4O8P
Molecular Weight
748.78
Precautions
H301, H311, H315, H319, H331, H335
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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